Francesco Cappello Selected Research

Chaperonin 60

1/2022	Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia.
1/2017	Exosomal HSP60: a potentially useful biomarker for diagnosis, assessing prognosis, and monitoring response to treatment.
9/2015	Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.
1/2013	Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60).
5/2012	Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
10/2005	Immunopositivity of heat shock protein 60 as a biomarker of bronchial carcinogenesis.

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Francesco Cappello Research Topics

Disease

55	Neoplasms (Cancer) 11/2022 - 03/2003
22	Carcinogenesis 01/2022 - 03/2003
14	Inflammation (Inflammations) 02/2019 - 07/2009
11	Chronic Obstructive Pulmonary Disease (COPD) 01/2020 - 03/2007
5	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2013
4	Insulin Resistance 01/2022 - 01/2015
4	Fatty Liver 01/2022 - 06/2012
4	COVID-19 11/2021 - 01/2020
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2015
4	Fibrosis (Cirrhosis) 10/2016 - 05/2014
4	Adenocarcinoma 09/2014 - 03/2003
3	Lung Neoplasms (Lung Cancer) 07/2022 - 06/2015
3	Obesity 01/2022 - 01/2015
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2015
3	Carcinoma (Carcinomatosis) 04/2021 - 09/2015
3	Virus Diseases (Viral Diseases) 01/2021 - 01/2013
3	Osteosarcoma (Osteogenic Sarcoma) 01/2020 - 01/2013
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2019 - 12/2013
3	Neoplasm Metastasis (Metastasis) 01/2017 - 09/2008
3	Ulcerative Colitis 06/2015 - 11/2010
2	Non-alcoholic Fatty Liver Disease 01/2022 - 06/2012
2	Liver Diseases (Liver Disease) 01/2022 - 01/2016
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 01/2014
2	Aneurysm (Aneurysms) 12/2021 - 03/2016
2	Seizures (Absence Seizure) 08/2021 - 03/2015
2	Hypertrophy 01/2021 - 01/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2020 - 02/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2015
2	Colorectal Neoplasms (Colorectal Cancer) 11/2019 - 02/2019
2	Dysbiosis 10/2019 - 12/2016
2	Colonic Neoplasms (Colon Cancer) 04/2019 - 01/2013
2	Glioma (Gliomas) 09/2018 - 06/2018
2	Papillary Thyroid Cancer 01/2017 - 08/2010
2	Disease Progression 01/2017 - 02/2016
2	Liver Cirrhosis (Hepatic Cirrhosis) 10/2016 - 01/2014
2	Thyroiditis 03/2015 - 05/2014
2	Infections 01/2015 - 01/2013
2	Myocardial Infarction 01/2013 - 05/2011
2	Heart Diseases (Heart Disease) 01/2013 - 03/2009
2	Hypoxia (Hypoxemia) 10/2011 - 08/2010
2	Ischemia 05/2011 - 05/2010
2	Heart Failure 07/2009 - 05/2009
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2022
1	Adenocarcinoma of Lung 07/2022
1	Cachexia 01/2022
1	Malnutrition (Nutritional Deficiencies) 01/2022
1	Muscular Atrophy (Muscle Atrophy) 01/2022
1	Insulinoma 01/2022

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 11/2022 - 06/2003
17	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2003
13	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2022 - 06/2003
13	Molecular Chaperones (Chaperone, Molecular)IBA 01/2022 - 07/2006
10	ChaperoninsIBA 01/2020 - 08/2009
7	Pharmaceutical PreparationsIBA 01/2022 - 05/2012
6	Biological ProductsIBA 01/2022 - 08/2009
6	Chaperonin 60IBA 01/2022 - 10/2005
6	CytokinesIBA 02/2019 - 02/2014
5	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2013
5	DNA (Deoxyribonucleic Acid)IBA 10/2016 - 07/2006
4	2-MethoxyestradiolIBA 07/2022 - 06/2015
4	Messenger RNA (mRNA)IBA 01/2022 - 08/2010
4	Histones (Histone)IBA 10/2016 - 01/2013
4	LipidsIBA 01/2016 - 01/2012
3	Tumor Biomarkers (Tumor Markers)IBA 07/2022 - 01/2014
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2022 - 03/2003
3	MicroRNAs (MicroRNA)IBA 12/2021 - 09/2018
3	3-nitrotyrosineIBA 11/2021 - 07/2009
3	AntibodiesIBA 01/2021 - 08/2012
3	Sirolimus (Rapamycin)FDA Link 11/2019 - 01/2017
3	SmokeIBA 01/2019 - 03/2007
3	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 08/2010
3	macroH2A histoneIBA 02/2016 - 01/2013
3	AntigensIBA 01/2016 - 05/2014
3	Heme Oxygenase-1IBA 01/2014 - 05/2011
2	Mercaptoethanol (2 Mercaptoethanol)IBA 07/2022 - 06/2015
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022 - 01/2015
2	Viral ProteinsIBA 01/2021 - 01/2020
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2020 - 01/2014
2	Metformin (Glucophage)FDA LinkGeneric 11/2019 - 02/2019
2	Ethanol (Ethyl Alcohol)IBA 04/2019 - 01/2016
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 05/2009
2	Interleukin-27 (Interleukin 27)IBA 01/2019 - 06/2014
2	Carrier Proteins (Binding Protein)IBA 01/2018 - 08/2009
2	Interleukin-8 (Interleukin 8)IBA 12/2017 - 01/2015
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017 - 01/2017
2	CollagenIBA 01/2017 - 05/2014
2	Interleukin-6 (Interleukin 6)IBA 06/2016 - 06/2014
2	Insulin (Novolin)FDA Link 12/2015 - 01/2015
2	Mitogen-Activated Protein KinasesIBA 01/2015 - 08/2010
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2013 - 07/2006
2	A-factor (Streptomyces)IBA 08/2010 - 09/2008
2	Mitochondrial DNA (mtDNA)IBA 04/2010 - 01/2010
2	Peroxidase (Myeloperoxidase)IBA 07/2009 - 05/2009
1	UbiquitinIBA 01/2022
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 01/2022
1	Azacitidine (5 Azacytidine)FDA Link 01/2022
1	Ligases (Synthetase)IBA 01/2022
1	Glial Fibrillary Acidic ProteinIBA 01/2022

Therapy/Procedure

20	Therapeutics 08/2021 - 04/2007
3	Drug Therapy (Chemotherapy) 02/2016 - 04/2013